3044am永利集团官方网站欢迎您的光临！
免费咨询热线： 4008-750-250
科研细胞
药靶细胞
标准品
NGS靶向捕获探针
DKK-1 Effector Reporter Cell
| CBP74200 | |
| I. Background | |
| DKK1, dickkopf WNT signaling pathway inhibitor 1, is a glycoprotein that acts to inhibit canonical Wnt signaling, and may play a role in cellular differentiation, proliferation, and apoptosis. Increased expression of Dkk1 is associated with metastasis in hilar cholangiocarcinoma, and both low and high levels of Dkk1 expression have been demonstrated in various tumor types, including lung cancer and hepatocellular carcinoma, respectively. | |
| II.Introduction | |
| Expressed gene: | DKK-1 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10%DMSO |
| Culture Medium: | DMEM+10%FBS+2ug/ml puromycin+100ug/ml hygromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
|
Figure 1.Dose Responese of DKK-1 Neutralization Ab to Rescue the Inhibition of Recombinant hWnt-3a Induced Reporter Activity by DKK-1 in DKK-1 Effector Reporter Cells (C11). |
|
扫一扫，关注我们公众号
Copyright ©2024 3044am永利集团 All Rights Reserved. 3044am永利集团版权所有 苏ICP备13038923号